Our latest version of MOLEonline brings many notable improvements, including:

• Replacement of deprecated LiteMol with the modern Mol* viewer,
• colour the tunnels in the 3D view according to their physicochemical properties,
• a new 2D view of the structure and calculated tunnels is generated by 2DProts,
• ability to store tunnels into the mmCIF file,
• ability to store and load computation settings.

Second version of ChannelsDB was published in Nucleic Acids Research Database Issue (see the ChannelsDB 2.0 paper). This version adds tunnels computed using both MOLE and CAVER and also features tunnels starting from cofactors within AlphaFill database.

Update to Chrome 75 disables WebGL functionalities important for MOLEonline LiteMol visualization. We are working on fix on this issue. Meanwhile, use other browsers for accessing MOLEonline.

We would like to announce that MOLEonline will not be available on Monday (December 17th) due to web server room maintenance. Sorry for the inconvenience.

Our paper, which describes the new features of MOLEonline, is accepted for publication in Web issue of Nucleic Acids Research.

The ChannelsDB database contains information about channel positions, geometry and physicochemical properties of reviewed and annotated channels from PDB database. It was published in Database issue of Nucleic Acids Research. You can reach ChannelsDB data available for queried PDB structure in Submission tab in right lower corner of MOLEonline GUI window.

Old version of MOLEonline 2.0 is still available at address: http://old.mole.upol.cz/